Contribution of Complement Activation on Kidney Injury
نویسندگان
چکیده
منابع مشابه
Role of complement activation in acute kidney injury
Acute kidney injury has an estimated incidence of 14.9–49.6 per 1000 patient years and may affect 13–18% of hospitalized patients. The incidence is increasing, and it is expected to double over the next decade [1–3]. AKI has been considered a self-limiting disease, with good prognosis when recovery is noted during admission [4], but several studies demonstrated that survivors of AKI may experie...
متن کاملRole of complement activation in acute kidney injury
Acute kidney injury has an estimated incidence of 14.9–49.6 per 1000 patient years and may affect 13–18% of hospitalized patients. The incidence is increasing, and it is expected to double over the next decade [1–3]. AKI has been considered a self-limiting disease, with good prognosis when recovery is noted during admission [4], but several studies demonstrated that survivors of AKI may experie...
متن کاملActivation of complement system in kidney after ketoprofen-induced kidney injury in sheep
BACKGROUND Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat inflammatory pain in humans and animals. An overdose of an NSAID is nephrotoxic and can lead to acute kidney injury (AKI). Complement activation occurs in several types of renal disorders with proteinuria. The aim of this study was to investigate whether complement system becomes activated in kidneys after a high...
متن کاملComplement activation and kidney injury molecule-1-associated proximal tubule injury in severe preeclampsia.
Kidney injury with proteinuria is a characteristic feature of preeclampsia, yet the nature of injury in specific regions of the nephron is incompletely understood. Our study aimed to use existing urinary biomarkers to describe the pattern of kidney injury and proteinuria in pregnancies affected by severe preeclampsia. We performed a case-control study of pregnant women from Brigham and Women's ...
متن کاملThe role of complement activation in rhabdomyolysis-induced acute kidney injury
Rhabdomyolysis (RM) may cause kidney damage and results primarily in acute kidney injury (AKI). Complement is implicated in the pathogenesis of renal diseases and ischemia-reperfusion injury (IRI), but the role of complement, especially its activation pathway(s) and its effect in RM-induced AKI, is not clear. This study established a rat model of AKI induced by RM via intramuscular treatment wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Nihon University Medical Association
سال: 2008
ISSN: 1884-0779,0029-0424
DOI: 10.4264/numa.67.272